Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen.
Gupta S, Subhedar NV, Bell JL, Field D, Bowler U, Hutchison E, Johnson S, Kelsall W, Pepperell J, Roberts T, Sinha S, Stanbury K, Wyllie J, Hardy P, Juszczak E; Baby-OSCAR Collaborative Group.
Gupta S, et al.
N Engl J Med. 2024 Jan 25;390(4):314-325. doi: 10.1056/NEJMoa2305582.
N Engl J Med. 2024.
PMID: 38265644
Free PMC article.
Clinical Trial.
RESULTS: A total of 326 infants were assigned to receive ibuprofen and 327 to receive placebo; 324 and 322, respectively, had data available for outcome analyses. A primary-outcome event occurred in 220 of 318 infants (69.2%) in the ibuprofen group and 202 of 318 infants ( …
RESULTS: A total of 326 infants were assigned to receive ibuprofen and 327 to receive placebo; 324 and 322, respectively, had data available …